Transcription Factor Regulatory Subnetworks

Search for subnetworks within the ChEA-KG GRN by entering one or two TFs. The background GRN contains 131,181 signed and directed TF-TF regulatory relationships between 1,559 target and 700 source human transcription factors.

Start with

Example:CHCHD3PITX3
End Node


Size:
Subnetwork of TFs Connected to LYL1
Please acknowledge ChEA-KG in your publications by citing the following reference:
Anna I. Byrd, John Erol Evangelista, Alexander Lachmann, Ho-Young Chung, Sherry L Jenkins, Avi Ma'ayan. ChEA-KG: Human Transcription Factor Regulatory Network with a Knowledge Graph User Interface.Preprint on bioRxiv (2025). doi:10.1101/2025.08.09.669505.

This website was prepared using the Ma’ayan Lab Knowledge Graph User Interface.
John Erol Evangelista, Andrew D. Lutsky, Anna I. Byrd, Daniel J. B. Clarke, Abinanda Prabhakaran, Sherry L. Jenkins, Avi Ma’ayan. Creating an Interactive Web Interface for Networks Stored in Knowledge Graph Databases. Current Protocols. 16 Sept 2025. https://doi.org/10.1002/cpz1.70200.
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