Transcription Factor Regulatory Subnetworks

Search for subnetworks within the ChEA-KG GRN by entering one or two TFs. The background GRN contains 131,181 signed and directed TF-TF regulatory relationships between 1,559 target and 700 source human transcription factors.

Start with

Example:CHCHD3PITX3
End Node


Size:
Subnetwork of TFs Connected to LYL1
Please acknowledge ChEA-KG in your publications by citing the following reference:
Anna I. Byrd, John Erol Evangelista, Andrew Van Dusen, Daniel J.B. Clarke, Maha Berrada, Sherry L Jenkins, Avi Ma'ayan. ChEA-KG and ChEA-KG-TS: a network-based transcription factor enrichment analysis tool with an accompanying time-series workflow. Nucleic Acids Research (2026). doi:10.1093/nar/gkag508.

This website was prepared using the Ma’ayan Lab Knowledge Graph User Interface.
John Erol Evangelista, Andrew D. Lutsky, Anna I. Byrd, Daniel J. B. Clarke, Abinanda Prabhakaran, Sherry L. Jenkins, Avi Ma’ayan. Creating an Interactive Web Interface for Networks Stored in Knowledge Graph Databases. Current Protocols. 16 Sept 2025. https://doi.org/10.1002/cpz1.70200.
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